Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311000 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7315609 | 0.91 | CRBN (0.52) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7315603 | 0.91 | CRBN (0.52) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11040553 | 0.82 | MEN1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ACRBN | |
| Hydrochloric Acid SCHEMBL11042578 | 0.82 | NR3C1 (0.53) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7288177 | 0.81 | GRIN2B (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2ACRBN | |
| SCHEMBL11067471 | 0.80 | MEN1 (0.60) | ALDH1A1MEN1KMT2ACRBNNR3C1 | |
| SCHEMBL7319943 | 0.79 | NR3C1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2ACRBN | |
| SCHEMBL7294275 | 0.79 | KMT2A (0.58) | ALDH1A1MEN1KMT2ACRBNMAPT | |
| SCHEMBL11043935 | 0.79 | CRBN (0.59) | ALDH1A1CRBNNR3C1PGRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845100-A | WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0202760-A2 | Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |