Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11759847 | 0.98 | TSHR (0.55) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL668582 | 0.87 | GPR35 (0.56) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL30131227 | 0.86 | TSHR (0.53) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL28031898 | 0.85 | GPR35 (0.54) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL5638935 | 0.84 | TSHR (0.58) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL10619013 | 0.84 | TSHR (0.58) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL9568264 | 0.82 | TSHR (0.56) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL8764130 | 0.82 | TSHR (0.56) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL30908227 | 0.82 | TSHR (0.56) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 | |
| SCHEMBL28104917 | 0.82 | TSHR (0.56) | TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234717-A | Bicyclic heteroaromatic compounds and their use as pest control agents | PI工业有限公司 | 2024-06-21 | — | — | CN | claimed |
| EP-2387557-B1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM SA (ES) | 2013-06-19 | — | — | EP | claimed |
| WO-2010099518-A2 | METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | WO | claimed |
| EP-1548069-B1 | Liquid formulations of direct dyes | BASF SE (DE) | 2010-08-04 | — | — | EP | claimed |
| US-7331998-B2 | Liquid formulations of direct dyes | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-19 | — | — | US | claimed |
| CN-100334255-C | Method for applying a phosphate covering and use of metal parts thus phospated | CHEMETALL GMBH (DE) | 2007-08-29 | — | — | CN | claimed |
| US-20050132510-A1 | Liquid formulations of direct dyes | BASF AKIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | US | claimed |
| CN-1196669-C | Method for producing substituted nitro benzoic acids by oxidation of corresponding nitro toluenes, nitro benzyl alcohols, esters and/or ethers | BAYER AG (DE) | 2005-04-13 | — | — | CN | claimed |
| EP-1274672-B1 | METHOD FOR PRODUCING SUBSTITUTED NITRO BENZOIC ACIDS BY OXIDATION OF CORRESPONDING NITRO TOLUENES, NITRO BENZYL ALCOHOLS, ESTERS AND/OR ETHERS | BAYER CHEMICALS AG (DE) | 2004-03-03 | — | — | EP | claimed |
| US-20040039227-A1 | Method for producing substituted nitro benzoic acids by oxidation of corresponding nitro toluenes, nitrol benzyl alcohols, esters and/or ethers | LANXESS DEUTSCHLAND GMBH (DE) | 2004-02-26 | — | — | US | claimed |
| EP-1099010-B1 | METHOD FOR RECOVERING PRECIOUS METALS | OTB OBERFLAECHENTECHNIK BERLIN (DE) | 2003-11-19 | — | — | EP | claimed |
| CN-1422243-A | Method for producing substituted nitro benzoic acids by oxidation of corresponding nitro toluenes, nitro benzyl alcohols, esters and/or ethers | BAYER AG (DE) | 2003-06-04 | — | — | CN | claimed |
| US-6160169-A | Preparation of amine salts of 4-nitrotoluene-2-sulfonic acid | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | claimed |
| EP-0460544-B1 | Process for the preparation of sulphonated anthranilic acids | BASF AG (DE) | 1995-08-09 | — | — | EP | claimed |
| EP-0380067-B1 | IMPROVED METHOD OF LUBRICATING IRON AND STEEL BEFORE COLD WORKING | HENKEL CORPORATION (US) | 1993-05-26 | — | — | EP | claimed |
| US-5196573-A | Process for the preparation of sulfonated anthranilic acids | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | claimed |
| EP-0380067-A1 | Improved method of lubricating iron and steel before cold working | HENKEL CORPORATION (US) | 1990-08-01 | — | — | EP | claimed |
| US-4680146-A | Process for the preparation of 4,4'-dinitrostilbene-2,2'-disulphonic acid salts | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-14 | — | — | US | claimed |
| CN-118234717-A | Bicyclic heteroaromatic compounds and their use as pest control agents | PI工业有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-3970505-A | POLYMERIZABLE ACRYLATE, THIOUREA, CURES THROUGH LARGE GAPS | LOCTITE CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039227-A1 | Method for producing substituted nitro benzoic acids by oxidation of corresponding nitro toluenes, nitrol benzyl alcohols, esters and/or ethers | NOS2, NOS1, CYP2E1 | TSHR 2883/4885SMN1; SMN2 2523/4885HSD17B10 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.