Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ME2 | P23368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581938 | 0.80 | GPR35 (0.43) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL12513926 | 0.79 | MEN1 (0.59) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29254661 | 0.73 | CYP1A2 (0.48) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL17707226 | 0.73 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL27670526 | 0.72 | PTPN1 (0.45) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2124452 | 0.72 | PTPN1 (0.67) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29473553 | 0.72 | PTPN1 (0.67) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL11629513 | 0.71 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL7308284 | 0.71 | HSP90AB1 (0.47) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL29254632 | 0.70 | SMN1; SMN2 (0.47) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |