Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | FCER2 | P06734 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 6/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311305 | 1.00 | LTA4H (0.44) | LTA4HMMP1FCER2MMEACE | |
| SCHEMBL7311365 | 1.00 | LTA4H (0.44) | LTA4HMMP1FCER2MMEACE | |
| SCHEMBL7309228 | 0.83 | LTA4H (0.47) | LTA4HMMP1FCER2MMEACE | |
| SCHEMBL7309261 | 0.83 | LTA4H (0.47) | LTA4HMMP1FCER2MMEACE | |
| SCHEMBL7311343 | 0.83 | REN (0.51) | REN | |
| SCHEMBL7309208 | 0.83 | LTA4H (0.47) | LTA4HMMP1FCER2MMEACE | |
| SCHEMBL7318538 | 0.83 | MME (0.45) | LTA4HMMEPOLB | |
| SCHEMBL7318567 | 0.83 | MME (0.45) | LTA4HMMEPOLB | |
| SCHEMBL7318511 | 0.83 | MME (0.45) | LTA4HMMEPOLB | |
| SCHEMBL7312785 | 0.77 | POLB (0.53) | CTSSALDH1A1HPGDPOLBCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |