Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ECE1 | P42892 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316387 | 0.84 | LMNA (0.47) | POLBKDM4EALDH1A1MAPK1NPSR1 | |
| SCHEMBL7316640 | 0.82 | KDM4E (0.40) | POLBKDM4EUSP2HSD17B10ECE1 | |
| SCHEMBL16724446 | 0.79 | POLB (0.45) | POLBKDM4EUSP2HSD17B10ECE1 | |
| SCHEMBL22954292 | 0.76 | CYP1A2 (0.38) | POLBKDM4EALDH1A1MAPK1NPSR1 | |
| SCHEMBL26231672 | 0.74 | CSNK1D (0.37) | POLBKDM4EUSP2HSD17B10ALDH1A1 | |
| SCHEMBL14354155 | 0.70 | NPSR1 (0.41) | POLBKDM4EHSD17B10ALDH1A1NPSR1 | |
| SCHEMBL7318992 | 0.69 | ECE1 (0.79) | KDM4EUSP2HSD17B10ECE1ALDH1A1 | |
| SCHEMBL7321910 | 0.69 | ECE1 (0.60) | POLBKDM4EHSD17B10ECE1ALDH1A1 | |
| SCHEMBL7322763 | 0.69 | ECE1 (0.79) | POLBKDM4EUSP2HSD17B10ADORA3 | |
| Methyl Syringate SCHEMBL211747 | 0.67 | MEN1 (0.61) | POLBKDM4EALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891892-A | Small molecule biaryl compounds as inhibitors of endothelin converting enzyme | WARNER-LAMBERT COMPANY (US) | 1999-04-06 | — | — | US | disclosed |