Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311341 | 0.82 | POLB (0.44) | KDM4EPOLBECE1ALDH1A1USP2 | |
| SCHEMBL16724446 | 0.77 | POLB (0.45) | KDM4EPOLBECE1ALDH1A1USP2 | |
| SCHEMBL22954292 | 0.71 | CYP1A2 (0.38) | KDM4EPOLBALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7316387 | 0.70 | LMNA (0.47) | KDM4EPOLBALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL503143 | 0.70 | MEN1 (0.58) | KDM4EMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21044526 | 0.70 | CYP4F2 (0.44) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL7318992 | 0.68 | ECE1 (0.79) | KDM4EECE1MEN1KMT2AALDH1A1 | |
| SCHEMBL733130 | 0.66 | MAPT (0.46) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL2305425 | 0.66 | MAPT (0.55) | KDM4EKMT2AALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL23703451 | 0.66 | PDCD1 (0.45) | KDM4EALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891892-A | Small molecule biaryl compounds as inhibitors of endothelin converting enzyme | WARNER-LAMBERT COMPANY (US) | 1999-04-06 | — | — | US | disclosed |