Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321536 | 0.91 | MTNR1A (0.41) | LTA4HALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL7324219 | 0.87 | MEN1 (0.42) | ALDH1A1LMNASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL7323187 | 0.85 | MTNR1A (0.48) | ALDH1A1HTTSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL7318337 | 0.85 | MEN1 (0.46) | ALDH1A1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL7324636 | 0.83 | ACLY (0.40) | PTPN1ALDH1A1LMNASMN1; SMN2MTNR1A | |
| SCHEMBL7323435 | 0.83 | F2 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2MTNR1A | |
| SCHEMBL7312999 | 0.82 | MEN1 (0.45) | ALDH1A1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL7317223 | 0.82 | GAA (0.41) | ALDH1A1LMNAHPGDSMN1; SMN2MTNR1A | |
| SCHEMBL7315999 | 0.82 | MEN1 (0.46) | ALDH1A1SMN1; SMN2MTNR1AMTNR1BMEN1 | |
| SCHEMBL7321080 | 0.82 | MAPT (0.45) | LMNAHTTSMN1; SMN2L3MBTL1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |