Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323187 | 0.88 | MTNR1A (0.48) | MEN1KMT2AALDH1A1GAAMTNR1A | |
| SCHEMBL7317223 | 0.86 | GAA (0.41) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL7324219 | 0.86 | MEN1 (0.42) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL7321536 | 0.85 | MTNR1A (0.41) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL7314673 | 0.84 | MEN1 (0.48) | MEN1KMT2AALDH1A1GAAMTNR1A | |
| SCHEMBL7321080 | 0.84 | MAPT (0.45) | MEN1KMT2AGAAPKMMTNR1A | |
| SCHEMBL7317547 | 0.83 | MEN1 (0.42) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL7323435 | 0.83 | F2 (0.42) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL7315938 | 0.83 | MEN1 (0.41) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL7311595 | 0.83 | LTA4H (0.42) | MEN1KMT2AALDH1A1GAAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |