Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311644 | 1.00 | KIF11 (0.38) | KIF11PTGS1SLC6A4SLC6A3PRKCZ | |
| SCHEMBL7320627 | 0.93 | BCAT2 (0.37) | KIF11PRKCZBCAT2PDK2SLC1A3 | |
| SCHEMBL7320630 | 0.93 | BCAT2 (0.37) | KIF11PRKCZBCAT2PDK2SLC1A3 | |
| SCHEMBL7322385 | 0.89 | HDAC4 (0.37) | KIF11BCAT2PTGS2PDK2MEN1 | |
| SCHEMBL7322395 | 0.89 | HDAC4 (0.37) | KIF11BCAT2PTGS2PDK2MEN1 | |
| SCHEMBL7317067 | 0.85 | KIF11 (0.38) | KIF11BCAT2PDK2SLC1A3SLC1A2 | |
| SCHEMBL7317072 | 0.85 | KIF11 (0.38) | KIF11BCAT2PDK2SLC1A3SLC1A2 | |
| SCHEMBL7323367 | 0.83 | KIF11 (0.34) | KIF11PDK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7323361 | 0.83 | KIF11 (0.34) | KIF11PDK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7323278 | 0.81 | KIF11 (0.49) | KIF11SLC6A4SLC6A3PDK2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |