Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322395 | 1.00 | HDAC4 (0.37) | HDAC4HDAC2HDAC8FGFR1SRC | |
| SCHEMBL7320630 | 0.92 | BCAT2 (0.37) | KIF11PDK2CYP2C19MEN1KMT2A | |
| SCHEMBL7320627 | 0.92 | BCAT2 (0.37) | KIF11PDK2CYP2C19MEN1KMT2A | |
| SCHEMBL7311653 | 0.89 | KIF11 (0.38) | KIF11PDK2CYP2C19MEN1KMT2A | |
| SCHEMBL7311644 | 0.89 | KIF11 (0.38) | KIF11PDK2CYP2C19MEN1KMT2A | |
| SCHEMBL7317072 | 0.84 | KIF11 (0.38) | KIF11PDK2CYP2C19MEN1KMT2A | |
| SCHEMBL7317067 | 0.84 | KIF11 (0.38) | KIF11PDK2CYP2C19MEN1KMT2A | |
| SCHEMBL7323361 | 0.82 | KIF11 (0.34) | KIF11PDK2CYP2C19MEN1KMT2A | |
| SCHEMBL7323367 | 0.82 | KIF11 (0.34) | KIF11PDK2CYP2C19MEN1KMT2A | |
| SCHEMBL7316108 | 0.82 | KIF11 (0.45) | KIF11PDK2KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |