Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.49 |
| ▸ | NAMPT | P43490 | 12/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323020 | 0.94 | MMP1 (0.49) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7323617 | 0.92 | MMP9 (0.57) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7325342 | 0.75 | NAMPT (0.56) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7352965 | 0.74 | MMP9 (0.44) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7322218 | 0.74 | NAMPT (0.55) | MMP1MMP9MMP13NAMPTALDH1A1 | |
| SCHEMBL7352954 | 0.72 | KAT6A (0.40) | MMP1MMP9MMP13ADAM17ALDH1A1 | |
| SCHEMBL7324688 | 0.72 | MMP1 (0.46) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7352961 | 0.71 | MMP13 (0.68) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7316683 | 0.71 | NAMPT (0.52) | MMP1MMP9MMP13ADAM17NAMPT | |
| SCHEMBL7316583 | 0.71 | NAMPT (0.53) | MMP1MMP9MMP13ADAM17NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |