Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.49 |
| ▸ | CTSK | P43235 | 12/20 | 0.48 |
| ▸ | CTSS | P25774 | 11/20 | 0.48 |
| ▸ | CTSB | P07858 | 7/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304422 | 0.93 | CTSL (0.50) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7314588 | 0.88 | CACNA1B (0.38) | CTSLCTSKCTSSCTSBCACNA1B | |
| SCHEMBL7309770 | 0.81 | EBP (0.44) | CTSLCTSKCTSS | |
| SCHEMBL7316501 | 0.81 | CTSL (0.44) | CTSLCTSKCTSSCTSBCACNA1B | |
| SCHEMBL7311694 | 0.81 | CTSL (0.44) | CTSLCTSKCTSSCTSBCACNA1B | |
| SCHEMBL7306148 | 0.81 | CTSL (0.51) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7313580 | 0.81 | FNTA (0.39) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7316235 | 0.81 | FNTA (0.39) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7312048 | 0.81 | FNTA (0.39) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7306274 | 0.81 | EBP (0.39) | CTSLCTSKCTSSCTSBCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |