Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576908 | 0.89 | REN (0.62) | RENMMP2MMP9MMP8 | |
| SCHEMBL7307799 | 0.89 | REN (0.75) | REN | |
| SCHEMBL7318638 | 0.89 | REN (0.75) | REN | |
| SCHEMBL7318357 | 0.87 | REN (0.69) | REN | |
| SCHEMBL10575916 | 0.85 | REN (0.61) | RENMMP2MMP9MMP8 | |
| SCHEMBL10572007 | 0.84 | REN (0.59) | RENMMP2MMP9MMP8 | |
| SCHEMBL10572900 | 0.82 | REN (0.52) | RENMMP2MMP9MMP8 | |
| SCHEMBL10579060 | 0.79 | REN (0.59) | RENMMP2MMP9MMP8 | |
| SCHEMBL10749774 | 0.75 | REN (0.66) | RENMMP2MMP9MMP8 | |
| SCHEMBL7307190 | 0.75 | REN (0.73) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135914-A | Controlling hypertension, hyperaldosteronism, and congestive heart failure | WARNER-LAMBERT COMPANY (US) | 1992-08-04 | — | — | US | disclosed |