Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.59 |
| ▸ | MMP2 | P08253 | 3/20 | 0.57 |
| ▸ | MMP9 | P14780 | 3/20 | 0.57 |
| ▸ | MMP8 | P22894 | 3/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579060 | 0.92 | REN (0.59) | RENMMP2MMP9MMP8 | |
| SCHEMBL10576908 | 0.87 | REN (0.62) | RENMMP2MMP9MMP8 | |
| SCHEMBL7301131 | 0.84 | KMT2A (0.49) | REN | |
| SCHEMBL2295759 | 0.84 | KMT2A (0.49) | REN | |
| SCHEMBL5709588 | 0.84 | KMT2A (0.49) | REN | |
| SCHEMBL7311764 | 0.84 | REN (0.64) | RENMMP2MMP9MMP8 | |
| SCHEMBL11981992 | 0.83 | REN (0.48) | RENMMP2MMP9MMP8 | |
| SCHEMBL13840602 | 0.83 | REN (0.48) | RENMMP2MMP9MMP8 | |
| SCHEMBL10575916 | 0.83 | REN (0.61) | RENMMP2MMP9MMP8 | |
| SCHEMBL10772819 | 0.83 | MMP2 (0.61) | MMP2MMP9MMP8HRH4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853463-A | Amino acid derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0216539-A2 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1987-04-01 | — | — | EP | disclosed |