Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 12/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 12/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313814 | 0.94 | CASP6 (0.36) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10376004 | 0.87 | PDE3B (0.38) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7320468 | 0.87 | PDE3B (0.38) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7303043 | 0.87 | CASP6 (0.35) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10376685 | 0.87 | PDE3B (0.41) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7320491 | 0.87 | L3MBTL1 (0.38) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10376981 | 0.86 | PDE3B (0.39) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7320624 | 0.86 | L3MBTL1 (0.37) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7311657 | 0.84 | L3MBTL1 (0.39) | CASP6PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10752635 | 0.83 | PDE3B (0.44) | CASP6PDE3BPDE3AP2RY12PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |