Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 12/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 12/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MC5R | P33032 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314783 | 0.94 | CASP6 (0.35) | CASP6PDE3BPDE3AL3MBTL1P2RY12 | |
| SCHEMBL10374677 | 0.88 | PDE3B (0.39) | CASP6PDE3BPDE3AL3MBTL1P2RY12 | |
| SCHEMBL7313849 | 0.87 | L3MBTL1 (0.39) | CASP6PDE3BPDE3AL3MBTL1P2RY12 | |
| SCHEMBL7311765 | 0.87 | CASP6 (0.35) | CASP6PDE3BPDE3AL3MBTL1P2RY12 | |
| SCHEMBL7315054 | 0.86 | L3MBTL1 (0.38) | CASP6PDE3BPDE3AL3MBTL1P2RY12 | |
| SCHEMBL7311484 | 0.83 | PDE3B (0.47) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7311657 | 0.83 | L3MBTL1 (0.39) | CASP6PDE3BPDE3AL3MBTL1P2RY12 | |
| SCHEMBL10374675 | 0.82 | PDE3B (0.39) | PDE3BPDE3AL3MBTL1P2RY12PDE4A | |
| SCHEMBL7320491 | 0.82 | L3MBTL1 (0.38) | CASP6PDE3BPDE3AL3MBTL1P2RY12 | |
| SCHEMBL7318852 | 0.82 | CASP6 (0.36) | CASP6PDE3BPDE3AL3MBTL1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |