Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320803 | 0.76 | REN (0.57) | REN | |
| SCHEMBL9523860 | 0.74 | REN (0.46) | REN | |
| SCHEMBL7314665 | 0.73 | REN (0.46) | REN | |
| SCHEMBL10653953 | 0.73 | REN (0.44) | REN | |
| SCHEMBL7309930 | 0.73 | REN (0.46) | REN | |
| SCHEMBL7319702 | 0.72 | REN (0.43) | REN | |
| SCHEMBL7326621 | 0.72 | REN (0.42) | REN | |
| SCHEMBL10420912 | 0.72 | REN (0.58) | REN | |
| Hydrochloric Acid SCHEMBL7323642 | 0.71 | REN (0.42) | REN | |
| SCHEMBL7316219 | 0.71 | REN (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135914-A | Controlling hypertension, hyperaldosteronism, and congestive heart failure | WARNER-LAMBERT COMPANY (US) | 1992-08-04 | — | — | US | disclosed |