Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305504 | 0.81 | PKM (0.49) | SMN1; SMN2TSHRPOLBALDH1A1ENPP2 | |
| SCHEMBL7303376 | 0.74 | TSHR (0.48) | SMN1; SMN2TSHRPOLBALDH1A1ENPP2 | |
| SCHEMBL7313228 | 0.73 | CNR1 (0.47) | SMN1; SMN2TSHRPOLBALDH1A1ENPP2 | |
| SCHEMBL4580127 | 0.72 | PKM (0.76) | SMN1; SMN2TSHRPOLBPKMPKLR | |
| SCHEMBL3343329 | 0.68 | PKM (0.58) | SMN1; SMN2TSHRPOLBALDH1A1PKM | |
| SCHEMBL7314488 | 0.65 | TSHR (0.55) | SMN1; SMN2TSHRPOLBALDH1A1PKM | |
| SCHEMBL2769910 | 0.64 | POLB (0.73) | SMN1; SMN2TSHRPOLBALDH1A1PKM | |
| SCHEMBL7309950 | 0.64 | TSHR (0.57) | SMN1; SMN2TSHRPOLBALDH1A1PKM | |
| SCHEMBL7301268 | 0.64 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRPOLBALDH1A1PKM | |
| SCHEMBL3300806 | 0.64 | TSHR (0.75) | SMN1; SMN2TSHRPOLBALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371074-A | Use of saccharin derivatives as proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-12-06 | — | — | US | claimed |
| EP-0542372-A1 | 2-Substituted saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-05-19 | — | — | EP | claimed |