Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315388 | 0.85 | ADRB2 (0.58) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7315445 | 0.85 | ADRB3 (0.56) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7312955 | 0.85 | ADRB2 (0.57) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7311030 | 0.84 | ADRB3 (0.55) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7314435 | 0.84 | ADRB3 (0.55) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7317896 | 0.84 | ADRB2 (0.56) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7309456 | 0.83 | ADRB3 (0.60) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7319624 | 0.83 | KMT2A (0.56) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7305119 | 0.81 | KMT2A (0.50) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL7311212 | 0.78 | ADRB2 (0.60) | KMT2AMEN1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | claimed |
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |