Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315445 | 0.94 | ADRB3 (0.56) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL7311030 | 0.93 | ADRB3 (0.55) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL7314435 | 0.93 | ADRB3 (0.55) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL7309456 | 0.92 | ADRB3 (0.60) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL7319624 | 0.92 | KMT2A (0.56) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL7311038 | 0.90 | ADRB2 (0.56) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL7309300 | 0.89 | KDM4E (0.48) | ADRB2ADRB1ADRB3KMT2AABCB1 | |
| SCHEMBL7319039 | 0.89 | ADRB2 (0.54) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL7315388 | 0.88 | ADRB2 (0.58) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL7305119 | 0.88 | KMT2A (0.50) | ADRB2ADRB1ADRB3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |