Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312955 | 0.94 | ADRB2 (0.57) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7314435 | 0.93 | ADRB3 (0.55) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7311030 | 0.93 | ADRB3 (0.55) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7319624 | 0.92 | KMT2A (0.56) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7309456 | 0.92 | ADRB3 (0.60) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7317896 | 0.88 | ADRB2 (0.56) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7315388 | 0.88 | ADRB2 (0.58) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7305119 | 0.86 | KMT2A (0.50) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7312116 | 0.85 | KMT2A (0.52) | ADRB3ADRB1ADRB2KMT2AMEN1 | |
| SCHEMBL7311038 | 0.84 | ADRB2 (0.56) | ADRB3ADRB1ADRB2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |