Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | CPA1 | P15085 | 2/20 | 0.54 |
| ▸ | CPA2 | P48052 | 2/20 | 0.54 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312238 | 1.00 | ACE (0.58) | ACEERAP2ERAP1LNPEPFOLH1 | |
| SCHEMBL6412335 | 0.87 | MMP1 (0.56) | ERAP2ERAP1LNPEPCPA1CPA2 | |
| SCHEMBL6412324 | 0.87 | MMP1 (0.56) | ERAP2ERAP1LNPEPCPA1CPA2 | |
| SCHEMBL7307608 | 0.85 | ERAP2 (0.62) | ACEERAP2ERAP1LNPEP | |
| SCHEMBL7342912 | 0.85 | ECE1 (0.54) | ACEERAP2ERAP1CPA1CPA2 | |
| SCHEMBL7305651 | 0.82 | MMP3 (0.52) | ACEERAP2ERAP1LNPEPCPA1 | |
| SCHEMBL6418666 | 0.82 | MMP1 (0.52) | CPA1CPA2CPA4MMP1 | |
| SCHEMBL6418679 | 0.82 | MMP1 (0.52) | CPA1CPA2CPA4MMP1 | |
| SCHEMBL7306489 | 0.81 | ERAP2 (0.68) | ACEERAP2ERAP1LNPEP | |
| SCHEMBL7312249 | 0.79 | ERAP2 (0.47) | ERAP2ERAP1LNPEPCPA1CPA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380921-A | Enzyme inhibitors for endothelin converting enzyme for cardiovascular disorders and atherosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0623625-A1 | Aminophosphonic acid derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |