Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310135 | 0.86 | LMNA (0.62) | LMNAALDH1A1GAAMAPTRAB9A | |
| SCHEMBL7298745 | 0.86 | HPGD (0.69) | LMNAALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL7312797 | 0.82 | CYP1A2 (0.67) | LMNAALDH1A1GAAMAPTMEN1 | |
| SCHEMBL1651693 | 0.78 | ALDH1A1 (1.00) | LMNAALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL11179944 | 0.77 | ALDH1A1 (0.96) | LMNAALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL7304587 | 0.77 | KDM4E (0.68) | LMNAALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27849040 | 0.76 | ALDH1A1 (0.54) | LMNAALDH1A1GAAMAPTRAB9A | |
| SCHEMBL1520334 | 0.75 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2GLAKDM4EPOLB | |
| SCHEMBL16442058 | 0.75 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2GLAKDM4EPOLB | |
| SCHEMBL7232912 | 0.75 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2GLAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |