SCHEMBL731241

SCHEMBL731241

COc1ccc(OC([NH])=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
CA1 P00915 6/20 0.52
CA2 P00918 6/20 0.52
CA12 O43570 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 2/20 0.50
PARP1 P09874 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
GAA P10253 3/20 0.48
ALDH1A1 P00352 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL708284 0.81 LMNA (0.64) LMNACYP1A2CYP2C9CYP2C19GAA
SCHEMBL5700480 0.80 CES2 (0.57) CES2CES1CA1CA2CA7
SCHEMBL7061292 0.80 CES2 (0.58) CES2CES1CA1CA2CA12
SCHEMBL1398350 0.80 CES2 (0.58) CES2CES1CA1CA2CA12
SCHEMBL4544926 0.79 CES2 (0.52) CES2CES1CA1CA2CA12
SCHEMBL7566178 0.78 MEN1 (0.48) CA1CA2CA12CA9CA14
SCHEMBL155983 0.78 LMNA (0.67) CES2CES1CA1CA2CA12
SCHEMBL1871227 0.78 LMNA (0.67) CES2CES1CA1CA2CA12
SCHEMBL56202 0.78 CES2 (0.56) CES2CES1CA1CA2CA12
SCHEMBL56203 0.78 CA1 (0.60) CES2CES1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024062843-A1 COLORED COMPOSITION, COLORED PRODUCT, AND COMPOUND 富士フイルム株式会社 2024-03-28 WO disclosed
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed
CN-116490574-A Compound, tautomer thereof or salt thereof, process for producing the same, coloring composition, method for dyeing, and dyed article 富士胶片株式会社 2023-07-25 CN disclosed
EP-3747956-A1 STAINING COMPOSITION, STAINED ARTICLE, AND AZO DYE FUJIFILM Corporation (JP) 2020-12-09 EP disclosed
US-20200354576-A1 DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT FUJIFILM CORPORATION (JP) 2020-11-12 US disclosed
WO-2019151451-A1 STAINING COMPOSITION, STAINED ARTICLE, AND AZO DYE 富士フイルム株式会社 2019-08-08 WO disclosed
EP-1407756-B2 Hair dye composition comprising methine dye KAO CORP (JP) 2016-09-28 EP disclosed
EP-1965255-B1 Color filter and method for making the color filter FUJIFILM CORP (JP) 2015-08-12 EP disclosed
EP-1975204-B1 Azo dye and azo compound FUJIFILM CORP (JP) 2013-10-02 EP disclosed
EP-1535599-B1 Method effecting a reversible colour change of dyed hair KAO CORP (JP) 2013-01-23 EP disclosed
US-5326681-A Dye forming couplers and silver halide color photosensitive material containing the same FUJI PHOTO FILM CO., LTD. (JP) 1994-07-05 US disclosed
US-5326682-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-07-05 US disclosed
EP-0565096-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-10-13 EP disclosed
EP-0563985-A1 Silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1993-10-06 EP disclosed
EP-0556700-A1 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-08-25 EP disclosed
EP-0545420-A2 Imidazole azo dyes and thermal transfer dye donating materials containing them FUJI PHOTO FILM CO., LTD. (JP) 1993-06-09 EP disclosed
EP-0518238-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1992-12-16 EP disclosed
EP-0244160-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL IMPROVED IN STABILITY OF DYE IMAGE KONICA CORPORATION (JP) 1990-10-17 EP disclosed
US-4914206-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-04-03 US disclosed
EP-0226896-A2 Lankacidin derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354576-A1 DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT CYP1B1, CYP1A1, NAT1 CES2 1219/4885CES1 695/4885CA1 1499/4885
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE AR, MAPT, NR5A1 CES2 3855/4885CES1 3442/4885CA1 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.