SCHEMBL708284

SCHEMBL708284

Cc1ccc(OC([NH])=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.64
ALDH1A1 P00352 1/20 0.50
GAA P10253 1/20 0.47
KMT2A Q03164 3/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ACHE P22303 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PTK2B Q14289 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 1/20 0.43
MMP13 P45452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL731241 0.81 CES2 (0.54) LMNAALDH1A1GAACYP1A2CYP2C9
SCHEMBL7064531 0.80 LMNA (0.70) LMNAALDH1A1GAAKMT2ACYP1A2
SCHEMBL47792 0.80 LMNA (0.70) LMNAALDH1A1GAAKMT2ACYP1A2
SCHEMBL4544923 0.79 LMNA (0.61) LMNAALDH1A1GAAKMT2ACYP1A2
SCHEMBL7566178 0.78 MEN1 (0.48) LMNAALDH1A1GAAKMT2ACYP3A4
SCHEMBL1254224 0.78 LMNA (0.67) LMNAALDH1A1GAAKMT2ACYP1A2
SCHEMBL577352 0.78 LMNA (0.74) LMNAALDH1A1GAAKMT2ACYP1A2
SCHEMBL280615 0.78 LMNA (1.00) LMNAALDH1A1GAAKMT2ACYP1A2
SCHEMBL11563871 0.77 LMNA (0.59) LMNAALDH1A1KMT2AL3MBTL1PTK2B
SCHEMBL97469 0.77 USP2 (0.60) LMNAALDH1A1KMT2AL3MBTL1PTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1865030-B1 DYE-CONTAINING HARDENABLE COMPOSITION, AND COLOR FILTER AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORP (JP) 2013-06-26 EP disclosed
US-8242103-B2 Sulphamides for treatment of cancer MERCK SHARP & DOHME LIMITED (GB) 2012-08-14 US disclosed
US-8124304-B2 Dye-containing curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-7709162-B2 Photosensitive composition, color filter, and its production method FUJIFILM CORPORATION (JP) 2010-05-04 US disclosed
US-20090197904-A1 Sulphamides for Treatment of Cancer MERCK SHARP & DOHME (UK) LIMITED (GB) 2009-08-06 US disclosed
US-20090049624-A1 DYE-CONTAINING CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
EP-1930339-A2 Imide compound MITSUI CHEMICALS, INC. (JP) 2008-06-11 EP disclosed
US-7365196-B2 Sulphonamido-substituted bridged bicycloalkyl derivatives MERCK SHARP & DOHME LTD. (GB) 2008-04-29 US disclosed
EP-1885349-A2 SULPHAMIDES FOR TREATMENT OF CANCER Merck Sharp & Dohme Limited (GB) 2008-02-13 EP disclosed
EP-0187521-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1986-07-16 EP disclosed
EP-0185506-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1986-06-25 EP disclosed
EP-0182486-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-05-28 EP disclosed
EP-0178794-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-04-23 EP disclosed
EP-0178165-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1986-04-16 EP disclosed
US-4241168-A TWO-EQUIVALENT MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-12-23 US disclosed
US-4237217-A IN WHICH COUPLING POSITION IS SUBSTITUTED WITH A SULFONAMIDO GROUP FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 US disclosed
US-4220470-A TWO-EQUIVALENT COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1980-09-02 US disclosed
US-4032346-A 5-OXO-2-PYRAZOLIN-4-YL-AMINE-CARBODITHIOATE-DITHIOCARBONATE FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US disclosed
US-4029508-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090197904-A1 Sulphamides for Treatment of Cancer SDHA, SDHB, BRDT LMNA 4362/4885ALDH1A1 357/4885GAA 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.