Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.63 |
| ▸ | CPA1 | P15085 | 4/20 | 0.55 |
| ▸ | CPA3 | P15088 | 2/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.47 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3104186 | 0.85 | TSHR (0.75) | KMOCPA1CPA3CPB1CPB2 | |
| SCHEMBL7315538 | 0.85 | TSHR (0.75) | KMOCPA1CPA3CPB1CPB2 | |
| SCHEMBL3113026 | 0.84 | KMO (0.63) | KMOCPA1CPA3CPB1CPB2 | |
| SCHEMBL7312457 | 0.83 | KMO (0.71) | KMOCPA1CPA3CPB1CPB2 | |
| SCHEMBL7321600 | 0.80 | KMO (0.59) | KMOCPA1CPA3CPB1CPB2 | |
| SCHEMBL2535661 | 0.79 | FOLH1 (0.68) | CPA1CPA3CPB1CPB2FOLH1 | |
| SCHEMBL7314484 | 0.79 | KMO (0.57) | KMOCPA1CPA3CPB1CPB2 | |
| SCHEMBL3104413 | 0.78 | KMO (0.68) | KMOCPA1CPA3CPB1CPB2 | |
| SCHEMBL7320178 | 0.78 | KMO (0.54) | KMOCPA1CPA3CPB1CPB2 | |
| SCHEMBL7316863 | 0.78 | ALDH1A1 (0.58) | KMOCPA1CPA3CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |