Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315272 | 0.78 | FBP1 (0.39) | NPC1RAB9AL3MBTL1MAPTTSHR | |
| SCHEMBL7312548 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2NPC1RAB9AMAPTTSHR | |
| SCHEMBL7306219 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2NPC1RAB9AL3MBTL1TSHR | |
| SCHEMBL3631173 | 0.74 | KAT2B (0.44) | SMN1; SMN2MAPTTSHRALDH1A1MEN1 | |
| SCHEMBL11740927 | 0.73 | TSHR (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL7311048 | 0.73 | FBP1 (0.44) | SMN1; SMN2NPC1RAB9AMAPTTSHR | |
| SCHEMBL27801706 | 0.72 | TSHR (0.46) | SMN1; SMN2L3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL10756385 | 0.72 | TSHR (0.48) | SMN1; SMN2L3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL13236290 | 0.70 | TSHR (0.50) | SMN1; SMN2L3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL8385612 | 0.70 | TSHR (0.43) | SMN1; SMN2NPC1RAB9AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31617-E | ANTICOAGULANTS; HYPOTENSIVE AND BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-3932407-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTICOAGULANTS | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |