Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316434 | 0.87 | MAPT (0.35) | MAPTL3MBTL1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7307522 | 0.85 | MAPT (0.35) | MAPTL3MBTL1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL10374597 | 0.74 | ERN1 (0.33) | MAPTL3MBTL1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7312566 | 0.73 | SMN1; SMN2 (0.43) | L3MBTL1KDM4ENPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10376145 | 0.72 | POLB (0.31) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7316139 | 0.68 | ALDH1A1 (0.31) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL31145936 | 0.67 | TDP1 (0.46) | MAPTL3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL7304380 | 0.66 | PDE3B (0.36) | — | |
| SCHEMBL7309546 | 0.65 | PDE3B (0.40) | — | |
| SCHEMBL7309670 | 0.63 | KDM4E (0.35) | MAPTL3MBTL1KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |