SCHEMBL731269

SCHEMBL731269

CC(=O)O[Si](CC(C)(C)C)(CC(C)(C)C)OC(C)=O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
ALDH1A1 P00352 3/20 0.31
HSD17B10 Q99714 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL731268 0.80 GAA (0.34) GAAALDH1A1HSD17B10LMNATSHR
SCHEMBL3890198 0.78 GAA (0.33) GAA
SCHEMBL133195 0.70 ALDH1A1 (0.41) ALDH1A1HSD17B10TDP1LMNATSHR
SCHEMBL705906 0.67 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1LMNATSHR
SCHEMBL706130 0.67 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1LMNATSHR
SCHEMBL702678 0.67 ALDH1A1 (0.38) ALDH1A1HSD17B10TDP1LMNATSHR
SCHEMBL21462896 0.65 ALDH1A1 (0.41) ALDH1A1TDP1TSHR
SCHEMBL6333013 0.65 GAA (0.31) GAA
SCHEMBL6699196 0.65 PAOX (0.33) ALDH1A1HSD17B10LMNA
SCHEMBL713405 0.65 ALDH1A1 (0.35) GAAALDH1A1HSD17B10LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8697561-B2 Microelectronic structure by selective deposition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-04-15 US disclosed
US-20120142182-A1 MICROELECTRONIC STRUCTURE BY SELECTIVE DEPOSITION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-06-07 US disclosed
US-8138100-B2 Microelectronic structure by selective deposition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-20 US disclosed
US-7816743-B2 Microelectronic structure by selective deposition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-10-19 US disclosed
US-7510939-B2 Microelectronic structure by selective deposition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-03-31 US disclosed
US-20090075439-A1 MICROELECTRONIC STRUCTURE BY SELECTIVE DEPOSITION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-03-19 US disclosed
US-20090072317-A1 MICROELECTRONIC STRUCTURE BY SELECTIVE DEPOSITION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-03-19 US disclosed
US-20080001225-A1 MICROELECTRONIC STRUCTURE BY SELECTIVE DEPOSITION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-01-03 US disclosed