Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309106 | 0.98 | NAAA (0.51) | NAAASIGMAR1EPHX1EPHX2CNR2 | |
| SCHEMBL7299667 | 0.94 | NAAA (0.46) | NAAASIGMAR1EPHX1EPHX2CNR2 | |
| SCHEMBL1678672 | 0.90 | NAAA (0.37) | NAAASIGMAR1CES2CES1 | |
| SCHEMBL1678747 | 0.89 | NAAA (0.40) | NAAASIGMAR1CES2CES1 | |
| SCHEMBL7303987 | 0.86 | CES2 (0.41) | NAAAEPHX1CES2CES1 | |
| SCHEMBL8386944 | 0.84 | NAAA (0.38) | NAAAEPHX1CES2CES1 | |
| SCHEMBL1679329 | 0.84 | HTT (0.35) | NAAACES2CES1 | |
| SCHEMBL8383242 | 0.80 | NAAA (0.34) | NAAAEPHX1CES2CES1 | |
| SCHEMBL7331382 | 0.78 | CES2 (0.44) | NAAAEPHX1CES2CES1 | |
| SCHEMBL7334716 | 0.78 | CES2 (0.44) | NAAAEPHX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728513-A | PHOTOGRAPHIC FILMS WITH SILVER IODOBROMIDE, SENSITIZER DYE AND COUPLER IN EMULSION | KONICA CORPORATION (JP) | 1998-03-17 | — | — | US | disclosed |
| US-5614519-A | (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists | KARL THOMAE GMBH (DE) | 1997-03-25 | — | — | US | disclosed |
| US-5602127-A | ADMINISTERING TO TREAT HYPERTENSION | KARL THOMAE GMBH (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5594003-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5591762-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0502314-A1 | Benzimidazol, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |