Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 4/20 | 0.34 |
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678747 | 0.98 | NAAA (0.40) | NAAASIGMAR1CES2CES1MEN1 | |
| SCHEMBL1679329 | 0.94 | HTT (0.35) | NAAAPKMCES2CES1MEN1 | |
| SCHEMBL7312858 | 0.90 | NAAA (0.49) | NAAASIGMAR1CES2CES1 | |
| SCHEMBL7309106 | 0.89 | NAAA (0.51) | NAAASIGMAR1BCHE | |
| SCHEMBL1679375 | 0.85 | — | — | |
| SCHEMBL7299667 | 0.84 | NAAA (0.46) | NAAASIGMAR1CES2CES1CYP1A2 | |
| SCHEMBL8386944 | 0.77 | NAAA (0.38) | NAAACES2CES1 | |
| SCHEMBL8383242 | 0.77 | NAAA (0.34) | NAAACES2CES1BCHE | |
| SCHEMBL7303987 | 0.75 | CES2 (0.41) | NAAACES2CES1 | |
| SCHEMBL1678457 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000012-B2 | Fungicide hydroximoyl-heterocycles derivatives | BAYER CROPSCIENCE AG (DE) | 2015-04-07 | — | — | US | claimed |
| US-20130040993-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-02-14 | — | — | US | claimed |
| EP-2519502-A2 | FUNGICIDAL HYDROXIMOYL-HETEROCYCLES DERIVATIVES | Bayer CropScience AG (DE) | 2012-11-07 | — | — | EP | claimed |
| WO-2011080254-A2 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | claimed |
| US-9000012-B2 | Fungicide hydroximoyl-heterocycles derivatives | BAYER CROPSCIENCE AG (DE) | 2015-04-07 | — | — | US | disclosed |
| US-20130040993-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-02-14 | — | — | US | disclosed |
| EP-2519502-A2 | FUNGICIDAL HYDROXIMOYL-HETEROCYCLES DERIVATIVES | Bayer CropScience AG (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080254-A2 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
| EP-1764075-A1 | TISSUE FACTOR PRODUCTION INHIBITOR | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | NAAA 1045/4885SIGMAR1 4028/4885PKM 2094/4885 |
| US-20130040993-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | HAAO, HPD, CYP51A1 | NAAA 387/4885SIGMAR1 4501/4885PKM 1990/4885 |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | NAAA 4495/4885SIGMAR1 706/4885PKM 3692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.