Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306126 | 0.96 | HTR2B (0.40) | HTR2BMAOBITGB3ITGA2BMAPK1 | |
| SCHEMBL7305668 | 0.89 | HTR2B (0.36) | HTR2BITGB3ITGA2BCCR2KCNH2 | |
| SCHEMBL7317060 | 0.89 | MAPK1 (0.37) | HTR2BITGB3ITGA2BMAPK1L3MBTL1 | |
| SCHEMBL7314575 | 0.89 | HTR2B (0.44) | HTR2BMAOBMAPK1L3MBTL1CCR2 | |
| SCHEMBL7311505 | 0.86 | HTR2B (0.44) | HTR2BMAOBITGB3ITGA2BMAPK1 | |
| SCHEMBL7307174 | 0.86 | MAPK1 (0.39) | HTR2BITGB3ITGA2BMAPK1L3MBTL1 | |
| SCHEMBL7303812 | 0.86 | MAOA (0.36) | HTR2BITGB3ITGA2BMAPK1L3MBTL1 | |
| SCHEMBL7314702 | 0.84 | SMN1; SMN2 (0.38) | HTR2BITGB3ITGA2BMAPK1L3MBTL1 | |
| SCHEMBL7300799 | 0.84 | HTR2B (0.44) | HTR2BMAOBITGB3ITGA2BMAPK1 | |
| SCHEMBL7316573 | 0.84 | ITGB3 (0.38) | HTR2BITGB3ITGA2BMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |