Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306892 | 0.93 | SMN1; SMN2 (0.41) | ITGB3ITGA2BHTR2BSMN1; SMN2HRH3 | |
| SCHEMBL7304262 | 0.91 | SMN1; SMN2 (0.34) | MAOAITGB3ITGA2BGLAHTR2B | |
| SCHEMBL7313685 | 0.90 | ITGB3 (0.42) | ITGB3ITGA2BHTR2BSMN1; SMN2HRH3 | |
| SCHEMBL7307174 | 0.89 | MAPK1 (0.39) | MAOAITGB3ITGA2BGLAHTR2B | |
| SCHEMBL7317060 | 0.89 | MAPK1 (0.37) | MAOAITGB3ITGA2BGLAHTR2B | |
| SCHEMBL7311239 | 0.89 | MAOA (0.35) | MAOAITGB3ITGA2BHTR2BSMN1; SMN2 | |
| SCHEMBL7313120 | 0.89 | ITGB3 (0.38) | MAOAITGB3ITGA2BGLAHTR2B | |
| SCHEMBL7303856 | 0.88 | MAPK1 (0.39) | MAOAPAOXGLAHTR2BSMN1; SMN2 | |
| SCHEMBL7314130 | 0.87 | ALDH1A1 (0.43) | HTR2BTSHRSIGMAR1ALDH1A1 | |
| SCHEMBL7313291 | 0.86 | HTR2B (0.40) | MAOAITGB3ITGA2BHTR2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |