Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635258 | 0.82 | ALDH1A1 (0.42) | DDB1CRBN | |
| SCHEMBL11435272 | 0.81 | DDB1 (0.41) | MAPK1SLC6A3DDB1CRBNGLA | |
| SCHEMBL8126802 | 0.80 | DDB1 (0.40) | MAPK1SLC6A3DDB1CRBNGLA | |
| SCHEMBL6737982 | 0.80 | DDB1 (0.40) | MAPK1SLC6A3DDB1CRBNGLA | |
| Hydrochloric Acid SCHEMBL5862748 | 0.79 | DDB1 (0.39) | MAPK1SLC6A3DDB1CRBNGLA | |
| SCHEMBL7318423 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL376160 | 0.77 | AKT1 (0.36) | DDB1CRBN | |
| SCHEMBL9763836 | 0.76 | ALDH1A1 (0.40) | HTTMAPK1SLC6A3DDB1CRBN | |
| SCHEMBL21874034 | 0.72 | KMT2A (0.37) | HDAC1HDAC2MAPTDDB1CRBN | |
| SCHEMBL8860733 | 0.72 | DDB1 (0.38) | DDB1CRBNGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115091-A1 | N-carboxyacyl derivatives of cyclic amino acids, useful as antihypertensives | ENI-Ente Nazionale Idrocarburi (IT) | 1984-08-08 | — | — | EP | disclosed |