Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126802 | 0.95 | DDB1 (0.40) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL6737982 | 0.95 | DDB1 (0.40) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| Hydrochloric Acid SCHEMBL5862748 | 0.94 | DDB1 (0.39) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL5635258 | 0.81 | ALDH1A1 (0.42) | ALDH1A1DDB1CRBN | |
| SCHEMBL7339530 | 0.81 | TDP1 (0.39) | ALDH1A1MAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL11435272 | 0.80 | DDB1 (0.41) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL376160 | 0.76 | AKT1 (0.36) | L3MBTL1DDB1CRBNTACR1 | |
| SCHEMBL7313309 | 0.76 | FFAR4 (0.38) | MAPK1DDB1CRBNGLAHTT | |
| SCHEMBL3660749 | 0.75 | DDB1 (0.48) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL8141759 | 0.75 | DDB1 (0.48) | ALDH1A1MAPK1L3MBTL1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439444-A2 | Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors | MONSANTO COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |
| US-5013842-A | Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors | MONSANTO COMPANY (US) | 1991-05-07 | — | — | US | disclosed |