Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677038 | 1.00 | HSP90AA1 (0.47) | HSP90AA1HPGDSLC18A3MAPTHCAR3 | |
| SCHEMBL27569116 | 0.88 | VCAM1 (0.51) | HSP90AA1HPGDSLC18A3MAPTHCAR3 | |
| SCHEMBL27953270 | 0.85 | HSP90AA1 (0.44) | HSP90AA1HPGDSLC18A3HCAR3ALDH1A1 | |
| SCHEMBL3901403 | 0.85 | HPGD (0.65) | HPGDMAPTHCAR3ALDH1A1MEN1 | |
| SCHEMBL11234314 | 0.84 | HCAR3 (0.48) | HSP90AA1HPGDSLC18A3HCAR3ALDH1A1 | |
| SCHEMBL11234316 | 0.84 | HCAR3 (0.48) | HSP90AA1HPGDSLC18A3HCAR3ALDH1A1 | |
| SCHEMBL11436734 | 0.84 | MEN1 (0.46) | HPGDSLC18A3MAPTALDH1A1MEN1 | |
| SCHEMBL2049760 | 0.82 | HTT (0.56) | HPGDSLC18A3MAPTALDH1A1MEN1 | |
| SCHEMBL15326534 | 0.82 | KMT2A (0.55) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12488269 | 0.81 | HPGD (0.59) | HPGDMAPTHCAR3ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266867-B2 | Piperidinyl monocarboxylic acids as S1P1 receptor agonists | BIOPROJET (FR) | 2016-02-23 | — | — | US | disclosed |
| EP-2697219-B1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | BIOPROJET SOC CIV (FR) | 2015-03-04 | — | — | EP | disclosed |
| EP-2697219-B1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | BIOPROJET SOC CIV (FR) | 2015-03-04 | — | — | EP | disclosed |
| US-20140099316-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2014-04-10 | — | — | US | disclosed |
| EP-2697219-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | Bioprojet (FR) | 2014-02-19 | — | — | EP | disclosed |
| WO-2012140020-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | BIOPROJET (FR) | 2012-10-18 | — | — | WO | disclosed |
| WO-2012140020-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | BIOPROJET (FR) | 2012-10-18 | — | — | WO | disclosed |
| EP-2511275-A1 | Novel piperidinyl monocarboxylic acids as S1P1 receptor agonists | BIOPROJET (FR) | 2012-10-17 | — | — | EP | disclosed |
| EP-2511275-A1 | Novel piperidinyl monocarboxylic acids as S1P1 receptor agonists | BIOPROJET (FR) | 2012-10-17 | — | — | EP | disclosed |
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |
| US-4263457-A | CATALYTIC DEHYDROGENATION | MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) | 1981-04-21 | — | — | US | disclosed |
| US-4016214-A | Preparation of ethynylbenzenes | WILLIAM H. RORER, INC. (US) | 1977-04-05 | — | — | US | disclosed |
| US-3952067-A | Ethynylbenzenes | WILLIAM H. RORER, INC. (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140099316-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | S1PR1, S1PR3, S1PR2 | HSP90AA1 3256/4885HPGD 2576/4885SLC18A3 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.