Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677038 | 0.84 | HSP90AA1 (0.47) | MEN1KMT2ASLC18A3ALDH1A1HPGD | |
| SCHEMBL7313448 | 0.84 | HSP90AA1 (0.47) | MEN1KMT2ASLC18A3ALDH1A1HPGD | |
| SCHEMBL11445603 | 0.79 | OPRL1 (0.50) | MEN1KMT2AALDH1A1HPGDSLC9A1 | |
| SCHEMBL11442373 | 0.79 | SLC9A1 (0.51) | ALDH1A1SLC9A1ADRA1DHTR2ASLC6A3 | |
| SCHEMBL14800306 | 0.76 | KMT2A (0.51) | MEN1KMT2AALDH1A1MAPTPKM | |
| SCHEMBL27430080 | 0.76 | VCAM1 (0.56) | MEN1KMT2ASLC18A3ALDH1A1HPGD | |
| SCHEMBL29404544 | 0.76 | MAPT (0.46) | MEN1KMT2AALDH1A1MAPTPKM | |
| SCHEMBL11445633 | 0.75 | QDPR (0.49) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL11965650 | 0.73 | HPGD (0.58) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL27569116 | 0.72 | VCAM1 (0.51) | MEN1KMT2ASLC18A3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039190-A1 | 2-(1-Piperazinyl)-4-pyrimidinamines and related compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-11-04 | — | — | EP | disclosed |
| US-4188396-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |