Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310024 | 0.82 | POLB (0.33) | KMT2A | |
| SCHEMBL7308333 | 0.76 | ADRA1A (0.40) | SMN1; SMN2CYP2C19HIF1AMEN1KMT2A | |
| SCHEMBL7307231 | 0.76 | CYP2C19 (0.38) | SMN1; SMN2ALDH1A1CYP2C19HIF1AMAPT | |
| SCHEMBL7315451 | 0.75 | PTGER4 (0.30) | PTGER4PTGER2 | |
| SCHEMBL7318358 | 0.70 | FFAR4 (0.38) | CYP2C19HIF1AMAPTRXFP1 | |
| SCHEMBL11009500 | 0.70 | SMN1; SMN2 (0.37) | PTGER3SMN1; SMN2ALDH1A1PTGER2MEN1 | |
| SCHEMBL11755090 | 0.68 | PTGER2 (0.38) | ALDH1A1PTGER2CYP2C19HIF1ARAB9A | |
| SCHEMBL17267375 | 0.66 | CYP2C19 (0.48) | SMN1; SMN2ALDH1A1CYP2C19HIF1AKMT2A | |
| SCHEMBL7308232 | 0.66 | CYP2C19 (0.39) | SMN1; SMN2ALDH1A1CYP2C19HIF1AMAPT | |
| SCHEMBL7304642 | 0.66 | EBP (0.54) | SMN1; SMN2CYP2C19HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |