Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.57 |
| ▸ | QPCT | Q16769 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14255015 | 0.89 | TBXAS1 (0.66) | ALDH1A1QPCTKMT2AMEN1KDM4E | |
| SCHEMBL14255017 | 0.89 | TBXAS1 (0.66) | ALDH1A1QPCTKMT2AMEN1KDM4E | |
| SCHEMBL21076446 | 0.85 | MGLL (0.62) | ALDH1A1QPCTKDM4E | |
| SCHEMBL11233244 | 0.81 | KMT2A (0.68) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL11383621 | 0.80 | TBXAS1 (0.76) | KMT2AMEN1TBXAS1 | |
| SCHEMBL15190312 | 0.80 | HPGD (0.69) | EGLN3QPCTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27425380 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1TP53KDM4E | |
| SCHEMBL1775043 | 0.78 | CYP1A2 (0.79) | ALDH1A1QPCTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL10457421 | 0.78 | MAPK1 (0.58) | ALDH1A1KMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL3255191 | 0.77 | TBXAS1 (0.78) | EGLN3TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |