Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314203 | 0.85 | KMT2A (0.33) | LTA4H | |
| SCHEMBL7772526 | 0.84 | NQO1 (0.36) | NQO1TP53CYP3A4ALDH1A1LTA4H | |
| SCHEMBL128399 | 0.81 | NQO1 (0.43) | NQO1TP53CYP3A4ALDH1A1LTA4H | |
| SCHEMBL7312733 | 0.80 | SMN1; SMN2 (0.32) | ALDH1A1 | |
| SCHEMBL11503774 | 0.78 | KCNH2 (0.32) | NQO1TP53CYP3A4LTA4H | |
| SCHEMBL3362979 | 0.77 | GABRA1 (0.33) | NQO1TP53CYP3A4ALDH1A1 | |
| SCHEMBL7768476 | 0.76 | NQO1 (0.36) | NQO1TP53CYP3A4ALDH1A1LTA4H | |
| SCHEMBL743598 | 0.74 | SMN1; SMN2 (0.38) | NQO1TP53CYP3A4ALDH1A1LTA4H | |
| SCHEMBL2962480 | 0.74 | NQO1 (0.37) | NQO1TP53CYP3A4ALDH1A1LTA4H | |
| SCHEMBL11612858 | 0.73 | TRPA1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634396-B1 | Amino acid derivatives and their use as inhibitors of encephalinase | BIOPROJET SOC CIV (FR) | 1998-10-28 | — | — | EP | disclosed |
| EP-0634396-A1 | Amino acid derivatives and their use as inhibitors of encephalinase | SOCIETE CIVILE BIOPROJET (FR) | 1995-01-18 | — | — | EP | disclosed |