Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456883 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL7313642 | 0.80 | NQO1 (0.33) | ALDH1A1 | |
| SCHEMBL18706209 | 0.79 | TAAR1 (0.32) | SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL18705840 | 0.79 | SMN1; SMN2 (0.32) | SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL11503610 | 0.78 | ALOX5 (0.32) | SMN1; SMN2 | |
| SCHEMBL18705611 | 0.78 | HTR7 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7314203 | 0.77 | KMT2A (0.33) | — | |
| SCHEMBL11612858 | 0.77 | TRPA1 (0.36) | ALDH1A1 | |
| SCHEMBL57641 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL18706347 | 0.76 | HTR7 (0.35) | SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634396-B1 | Amino acid derivatives and their use as inhibitors of encephalinase | BIOPROJET SOC CIV (FR) | 1998-10-28 | — | — | EP | disclosed |
| EP-0634396-A1 | Amino acid derivatives and their use as inhibitors of encephalinase | SOCIETE CIVILE BIOPROJET (FR) | 1995-01-18 | — | — | EP | disclosed |