Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 6/20 | 0.51 |
| ▸ | ANPEP | P15144 | 2/20 | 0.51 |
| ▸ | ECE1 | P42892 | 7/20 | 0.50 |
| ▸ | IL1RN | P18510 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | PYGB | P11216 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313675 | 0.92 | ECE1 (0.61) | ERAP2ERAP1ANPEPECE1IL1RN | |
| SCHEMBL7312422 | 0.87 | ECE1 (0.56) | ERAP2ERAP1ANPEPECE1IL1RN | |
| SCHEMBL7313702 | 0.85 | ECE1 (0.61) | ERAP2ERAP1ANPEPECE1IL1RN | |
| SCHEMBL8200511 | 0.83 | KDM4E (0.51) | ERAP2ERAP1ANPEPECE1IL1RN | |
| SCHEMBL3098144 | 0.81 | ITGB2 (0.47) | TP53ACE | |
| SCHEMBL7306796 | 0.81 | ECE1 (0.65) | ERAP2ERAP1ANPEPECE1IL1RN | |
| SCHEMBL27459375 | 0.81 | ECE1 (0.65) | ERAP2ERAP1ANPEPECE1IL1RN | |
| SCHEMBL8200899 | 0.80 | ERAP1 (0.67) | ERAP2ERAP1ANPEPECE1IL1RN | |
| SCHEMBL8908474 | 0.79 | ERAP2 (0.56) | ERAP2ERAP1ECE1IL1RN | |
| SCHEMBL7305118 | 0.78 | ECE1 (0.68) | ERAP2ERAP1ANPEPECE1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691985-B1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMA INC (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5608078-A | Phosphonomethyldipeptides and process for preparation thereof | MERRELL PHARMACEUTICALS INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0691985-A1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022908-A1 | PHOSPHONOMETHYLDIPEPTIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0618224-A1 | Phosphonomethyldipeptides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-05 | — | — | EP | disclosed |