Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313746 | 1.00 | KIF11 (0.42) | KIF11PPARGPPARASLC1A3SLC1A2 | |
| SCHEMBL7323718 | 0.86 | PDK2 (0.40) | KIF11SLC1A3SLC1A2SLC1A1PDK2 | |
| SCHEMBL7323711 | 0.86 | PDK2 (0.40) | KIF11SLC1A3SLC1A2SLC1A1PDK2 | |
| SCHEMBL7313476 | 0.82 | PDK2 (0.36) | SLC1A3SLC1A2SLC1A1PDK2SLC6A9 | |
| SCHEMBL7313467 | 0.82 | PDK2 (0.36) | SLC1A3SLC1A2SLC1A1PDK2SLC6A9 | |
| SCHEMBL7325808 | 0.75 | KIF11 (0.38) | KIF11PPARGPPARASLC1A3SLC1A2 | |
| SCHEMBL7325812 | 0.75 | KIF11 (0.38) | KIF11PPARGPPARASLC1A3SLC1A2 | |
| SCHEMBL7315698 | 0.75 | SLC1A3 (0.43) | KIF11PPARGPPARASLC1A3SLC1A2 | |
| SCHEMBL7315704 | 0.75 | SLC1A3 (0.43) | KIF11PPARGPPARASLC1A3SLC1A2 | |
| SCHEMBL7317367 | 0.75 | KIF11 (0.44) | KIF11SLC1A3SLC1A2SLC1A1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |