Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309173 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL7338817 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL7319267 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL7317082 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL7336551 | 0.76 | F2 (0.41) | KMT2AHPGDDPP4 | |
| SCHEMBL7327687 | 0.74 | F2 (0.41) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7322630 | 0.73 | L3MBTL1 (0.39) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL7312251 | 0.73 | POLB (0.42) | ALDH1A1MEN1KMT2AHPGDACHE | |
| SCHEMBL7316493 | 0.73 | HSD11B1 (0.42) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL13663708 | 0.66 | NPC1 (0.62) | ALDH1A1MEN1KMT2ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371091-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5332822-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-07-26 | — | — | US | disclosed |