Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.46 |
| ▸ | RELA | Q04206 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317381 | 0.87 | HTR1A (0.56) | NFKB1NFKB2RELAHTR1AHTR1D | |
| SCHEMBL7321215 | 0.87 | HTR1A (0.56) | NFKB1NFKB2RELAHTR1AHTR1D | |
| SCHEMBL7318030 | 0.87 | HTR1A (0.56) | NFKB1NFKB2RELAHTR1AHTR1D | |
| SCHEMBL7307892 | 0.87 | HTR1A (0.56) | NFKB1NFKB2RELAHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL467043 | 0.86 | HTR1A (0.55) | NFKB1NFKB2RELAHTR1AHTR1D | |
| SCHEMBL7116097 | 0.82 | NFKB1 (0.57) | NFKB1NFKB2RELA | |
| SCHEMBL7116091 | 0.82 | NFKB1 (0.57) | NFKB1NFKB2RELA | |
| SCHEMBL7114684 | 0.81 | KDM4E (0.38) | NFKB1NFKB2RELAHTR1AHTR1D | |
| SCHEMBL7114678 | 0.81 | KDM4E (0.38) | NFKB1NFKB2RELAHTR1AHTR1D | |
| SCHEMBL7309189 | 0.80 | NFKB1 (0.44) | NFKB1NFKB2RELAHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318988-A | Treating psychoses | BAYER AKTIENGESELLSCHAFT (DE) | 1994-06-07 | — | — | US | claimed |