Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27325072 | 0.85 | LMNA (0.38) | ESR2CTSLCTSBCTSKHRH3 | |
| SCHEMBL27448307 | 0.77 | ESR2 (0.41) | ESR2HRH3 | |
| SCHEMBL7314041 | 0.77 | GRM2 (0.43) | ESR2CTSLCTSBCTSKCTSV | |
| SCHEMBL7314032 | 0.77 | GRM2 (0.43) | ESR2CTSLCTSBCTSKCTSV | |
| SCHEMBL27310571 | 0.75 | PDE4A (0.38) | ESR2HRH3 | |
| SCHEMBL27310569 | 0.75 | PDE4A (0.38) | ESR2HRH3 | |
| SCHEMBL7753890 | 0.72 | ESR2 (0.47) | ESR2CTSLCTSBCTSKPSEN1 | |
| SCHEMBL27319008 | 0.69 | PDE4A (0.40) | ESR2 | |
| SCHEMBL7308062 | 0.69 | GRM2 (0.50) | — | |
| SCHEMBL7308070 | 0.69 | GRM2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051308-C | Oxazolidin-2-one derivatives | HOFFMANN LA ROCHE (CH) | 2000-04-12 | — | — | CN | disclosed |
| CN-1109054-A | Oxazolidin-2-one derivatives | HOFFMANN LA ROCHE (CH) | 1995-09-27 | — | — | CN | disclosed |