Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 19/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304839 | 0.83 | CACNA1G (0.44) | CACNA1GKCNH2KCNN4CACNA1C | |
| SCHEMBL4963270 | 0.79 | KCNN4 (0.53) | CACNA1GKCNH2KCNN4CACNA1C | |
| SCHEMBL888286 | 0.78 | KCNN4 (0.51) | CACNA1GKCNH2KCNN4CACNA1C | |
| SCHEMBL7307231 | 0.75 | CYP2C19 (0.38) | KCNN4 | |
| SCHEMBL7313602 | 0.73 | KCNH2 (0.37) | KCNH2KCNN4 | |
| SCHEMBL1886552 | 0.72 | CACNA1G (0.58) | CACNA1GKCNH2CACNA1C | |
| SCHEMBL7308792 | 0.72 | CYP2C19 (0.38) | — | |
| SCHEMBL9449505 | 0.71 | HDAC3 (0.45) | KCNN4 | |
| SCHEMBL9449951 | 0.71 | HDAC3 (0.45) | KCNN4 | |
| SCHEMBL17267375 | 0.71 | CYP2C19 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |