Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 17/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314042 | 0.83 | CACNA1G (0.46) | CACNA1GKCNH2KCNN4CACNA1C | |
| SCHEMBL4963270 | 0.76 | KCNN4 (0.53) | CACNA1GKCNH2KCNN4MAPTCACNA1C | |
| SCHEMBL7309814 | 0.75 | ALDH1A1 (0.38) | KCNH2MAPTALDH1A1 | |
| SCHEMBL888286 | 0.75 | KCNN4 (0.51) | CACNA1GKCNH2KCNN4CACNA1CALDH1A1 | |
| SCHEMBL7316634 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7314258 | 0.72 | CHRM2 (0.37) | MAPTALDH1A1GAA | |
| SCHEMBL7317285 | 0.70 | CHRM3 (0.33) | ALDH1A1 | |
| SCHEMBL3999764 | 0.70 | ALDH1A1 (0.67) | KCNN4MAPTALDH1A1GAA | |
| SCHEMBL7308732 | 0.70 | CHRM3 (0.32) | KCNH2 | |
| SCHEMBL1886552 | 0.69 | CACNA1G (0.58) | CACNA1GKCNH2CACNA1CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |