Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313523 | 1.00 | CTSK (0.43) | CTSKL3MBTL1SIRT2CTSLCCR6 | |
| SCHEMBL8083648 | 0.89 | L3MBTL1 (0.40) | L3MBTL1SIRT2CTSLCCR6PAX8 | |
| SCHEMBL7265609 | 0.81 | L3MBTL1 (0.46) | L3MBTL1CCR6PAX8MAPT | |
| SCHEMBL7318212 | 0.77 | FOLH1 (0.58) | SIRT2 | |
| SCHEMBL7311020 | 0.77 | FOLH1 (0.58) | SIRT2 | |
| SCHEMBL6620920 | 0.75 | L3MBTL1 (0.43) | L3MBTL1CCR6PAX8MAPT | |
| SCHEMBL6620321 | 0.74 | L3MBTL1 (0.46) | L3MBTL1CCR6PAX8HDAC3HDAC1 | |
| SCHEMBL7310882 | 0.74 | TACR1 (0.39) | CTSKCTSLMAPT | |
| SCHEMBL30882671 | 0.74 | OPRK1 (0.49) | MAPT | |
| SCHEMBL30882505 | 0.74 | OPRK1 (0.49) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |