SCHEMBL731428

SCHEMBL731428

Nc1[c]c2ccccc2cc1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.36
PDPK1 O15530 1/20 0.35
POLB P06746 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP3A4 P08684 4/20 0.34
ALDH1A1 P00352 4/20 0.34
HSD17B10 Q99714 3/20 0.34
HPGD P15428 2/20 0.34
TSHR P16473 1/20 0.34
KEAP1 Q14145 1/20 0.34
KMT2A Q03164 3/20 0.33
ALOX15 P16050 2/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
NPC1 O15118 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
HPRT1 P00492 1/20 0.33
HBB P68871 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10822441 0.78 BRD4 (0.37) PDPK1CYP3A4ALDH1A1HSD17B10TSHR
SCHEMBL11764391 0.78 TRPM4 (0.39) PDPK1CYP3A4ALDH1A1HSD17B10HPGD
SCHEMBL76620 0.78 IDO1 (0.34) IDO1PDPK1POLBSMN1; SMN2CYP3A4
SCHEMBL11764397 0.78 IDO1 (0.38) IDO1PDPK1POLBSMN1; SMN2CYP3A4
SCHEMBL7305067 0.76 ALDH1A1 (0.38) POLBSMN1; SMN2CYP3A4ALDH1A1HSD17B10
SCHEMBL24252 0.75 CYP2A6 (0.41) PDPK1CYP3A4ALDH1A1HSD17B10HPGD
SCHEMBL16161201 0.74 ALDH1A1 (0.41) IDO1PDPK1POLBSMN1; SMN2CYP3A4
SCHEMBL2251306 0.72 ALDH1A1 (0.40) PDPK1POLBSMN1; SMN2CYP3A4ALDH1A1
SCHEMBL2252110 0.72 ALDH1A1 (0.50) PDPK1POLBSMN1; SMN2CYP3A4ALDH1A1
SCHEMBL28076506 0.72 ALDH1A1 (0.39) PDPK1CYP3A4ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138130-B2 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE COMPANY LLC (US) 2012-03-20 US claimed
EP-1707616-B1 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE CO (US) 2011-06-22 EP claimed
US-20060223717-A1 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE COMPANY LLC 2006-10-05 US claimed
EP-1707616-A2 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants Chevron Oronite Company LLC (US) 2006-10-04 EP claimed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US claimed
WO-2024135508-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2024-06-27 WO disclosed
WO-2023167234-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2023-09-07 WO disclosed
EP-3336124-A1 POLYARYLENE COMPOSITIONS AND METHODS Rohm and Haas Electronic Materials LLC (US) 2018-06-20 EP disclosed
EP-3336125-A1 POLYARYLENE RESIN COMPOSITIONS Rohm and Haas Electronic Materials LLC (US) 2018-06-20 EP disclosed
US-20180162967-A1 POLYARYLENE RESIN COMPOSITIONS ROHM & HAAS ELECT MAT (US) 2018-06-14 US disclosed
US-20180162992-A1 POLYARYLENE COMPOSITIONS AND METHODS ROHM & HAAS ELECT MAT (US) 2018-06-14 US disclosed
US-8993349-B2 Method for enhancing transport of semiconductor nanocrystals across biological membranes Life Technologies Corporation (US) 2015-03-31 US disclosed
EP-0437016-A2 Lipid A analogues having immunoactivating and anti-tumour activity Sankyo Company Limited (JP) 1991-07-17 EP disclosed
CN-1052481-A Lipoid category-A with immunocompetence and anti-tumor activity is like thing SANKYO CO (JP) 1991-06-26 CN disclosed
EP-0094050-B1 ULTRATHIN FILM, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF FOR CONCENTRATING A SPECIFIED GAS IN A GASEOUS MIXTURE TEIJIN LIMITED (JP) 1989-09-27 EP disclosed
US-4644046-A BLEND OF SILICON CONTAINING POLYAMINE, POLYSILOXANE, AND DIISOCYNATE GROUP TEIJIN LIMITED (JP) 1987-02-17 US disclosed
US-4493714-A SILICON CONTAINING POLYUREAS TEIJIN LIMITED (JP) 1985-01-15 US disclosed
US-4472300-A ANTIMICROBIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-09-18 US disclosed
EP-0094050-A2 Ultrathin film, process for production thereof, and use thereof for concentrating a specified gas in a gaseous mixture TEIJIN LIMITED (JP) 1983-11-16 EP disclosed
US-4207234-A 4-Unsubstituted azetidinone derivatives and process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180162967-A1 POLYARYLENE RESIN COMPOSITIONS PARG, PUF60, PCBP1 IDO1 3512/4885PDPK1 4579/4885POLB 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.